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Nexopamil racemate
😃Good
Catalog No. T12215Cas No. 116759-35-4
Alias (Rac)-Nexopamil
Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.
Nexopamil racemate
😃Good
Purity: 98.61%
Catalog No. T12215Alias (Rac)-NexopamilCas No. 116759-35-4
Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $700 | 6-8 weeks | |
| 5 mg | $1,800 | 6-8 weeks |
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Purity:98.61%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity. |
| Targets&IC50 | PRP:81 nM |
| In vitro | In vitro, Nexopamil most potently inhibits serotonin-induced platelet aggregation in dog platelet-rich plasma (PRP) with an IC50 of 81 nM [1]. |
| In vivo | Within the first 30 minutes after application, Nexopamil (0.05 mg/kg) completely abolishes cyclic flow reductions (CFRs) without significantly altering hemodynamics [1]. |
| Alias | (Rac)-Nexopamil |
| Molecular Weight | 404.59 |
| Formula | C24H40N2O3 |
| Cas No. | 116759-35-4 |
| Smiles | N#CC(C1=CC(OC)=C(OC)C(OC)=C1)(CCCN(C)CCCCCC)C(C)C |
| Relative Density. | 0.985 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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